Knowing the Gene Doping.

The gene is the biologic unit of the heredity and they are simplified codes for the protein synthesis. In some cases, these genes are defective and have wrong information that entail a lack or viceverse in the protein synthesis. In this join, the genetic therapy will try to repair the defective gene. But in the same way, it will be possible modify the genes with the purpose of achieve a biological advantange that can enhance the sport performance.

That fact cause that the WADA considered the gene doping as a ilegal method in the prohibid list. The following procedures are consider by the WADA as prohibited, since they have the potential to enhance performance:

1. The use of polymers of nucleic acids or nucleic acid analogues.

 2. The use of gene editing agents designed to alter genome sequences and/or the transcriptional or epigenetic regulation of gene expression.

3. The use of normal or genetically modified cells

However, is not easy to detec that genes have been modified. In the physical activity context there are several genes that carry the information of enhance endurance (EPO) or proteins which increase the muscle mass (Growth hormone).

Nowadays, the genetic therapy is not aprobed medically since could deliver in nocive effect. In a short term, this method can produce hard inmune-respone that could cause the death or the development of diseases as leukemia. In the long term, due to the lack of control of the gene expression, the integrates genes could produce substances althoug they are not required, which could increase the risk of tumours or lead to cardiovascular problems.